@article {2373, title = {Leishmania DNA Replication Timing: A Stochastic Event?}, journal = {Trends Parasitol}, volume = {32}, year = {2016}, month = {2016 10}, pages = {755-757}, abstract = {

For eukaryotic genomes, DNA synthesis initiates at multiple discrete regions known as replication origins in a dynamic yet regulated manner to ensure genomic stability. Two recent studies using different approaches reveal few Leishmania origins and that origin firing may proceed in a mainly stochastic manner.

}, keywords = {Animals, DNA Replication Timing, Drug Delivery Systems, Genomic Instability, Humans, Leishmania, Leishmaniasis, Replication Origin}, issn = {1471-5007}, doi = {10.1016/j.pt.2016.05.011}, author = {Rocha-Granados, Maria C and Klingbeil, Michele M} }