MacA, a diheme c-type cytochrome involved in Fe(III) reduction by Geobacter sulfurreducens.

TitleMacA, a diheme c-type cytochrome involved in Fe(III) reduction by Geobacter sulfurreducens.
Publication TypeJournal Article
Year of Publication2004
AuthorsButler JE, Kaufmann F, Coppi MV, Núñez C, Lovley DR
JournalJ Bacteriol
Volume186
Issue12
Pagination4042-5
Date Published2004 Jun
ISSN0021-9193
KeywordsAmino Acid Sequence, Bacterial Proteins, Cytochrome c Group, Deltaproteobacteria, Electron Transport, Ferric Compounds, Gene Deletion, Molecular Sequence Data, Oxidation-Reduction
Abstract

A 36-kDa diheme c-type cytochrome abundant in Fe(III)-respiring Geobacter sulfurreducens, designated MacA, was more highly expressed during growth with Fe(III) as the electron acceptor than with fumarate. Although MacA has homology to proteins with in vitro peroxidase activity, deletion of macA had no impact on response to oxidative stress. However, the capacity for Fe(III) reduction was greatly diminished, indicating that MacA, which is predicted to be localized in the periplasm, is a key intermediate in electron transfer to Fe(III).

DOI10.1128/JB.186.12.4042-4045.2004
Alternate JournalJ. Bacteriol.
PubMed ID15175321